[Study of lipid peroxidation in patients with chronic renal failure]

The levels of lipid peroxide in plasma and erythrocyte membrane, the contents of blood superoxide dismutase and copper, zinc, iron in plasma, and erythrocyte membrane fluidity were investigated in patients with chronic renal failure (CRF). In comparison with the health subjects the levels of lipid peroxide in plasma and erythrocyte membrane were significantly higher, the contents of blood superoxide dismutase were significantly lower in the patients with CRF. The plasma copper increased and plasma zinc decreased, but plasma iron remained unchanges in the patients of CRF. We found that rises of lipid peroxide in erythrocyte membrane were closely related to changes of microviscosity in them.