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Sleep apnea and REM sleep behavior disorder in patients with Chiari malformations
Paulo Sérgio A Henriques-Filho1, Riccardo Pratesi
1Program in Medical Sciences, School of Medicine, Brasilia University, Brasilia, Brazil. pazeredo@linkexpress.com.br
Background:
Chiari malformations (CM) may result in the appearance of REM sleep behavior disorder (RBD) and sleep apnea syndrome (SAS) that can be considered markers of brain stem dysfunction.
Purpose:
To evaluate the frequency of RBD and SAS in patients with CM type I and II.
Method:
Were evaluated 103 patients with CM by means of full night polysomnography. Were scoring different sleep stages, frequency of abnormal movements (through video monitoring) and abnormal respiratory events.
Results:
Of the 103 patients, 36 showed CM type I and 67 CM type II. Episodes of RBD were observed in 23 patients. Abnormal apnea-hypopnea index (AHI) was observed in 65 patients.
Conclusion:
The high rate of RBD suggests that this parassomnia and the increased frequency of central sleep apnea episodes, may be considered as a marker of progressive brain stem dysfunction.
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