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Updated: Jul 3, 2026

A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma
Published on: January 5, 2017
Synovial sarcoma of the head and neck: rare case of cervical metastasis
Hiroto Ishiki1, Chie Miyajima, Kazunari Nakao
1Division of Head and Neck Surgery, Shizuoka Cancer Center, Shizuoka, Japan. h.ishiki@scchr.jp
Background:
Synovial sarcoma is a rarely encountered soft tissue sarcoma. Surgery with a wide surgical margin is the treatment of choice. However, there is no consensus on the treatment of head and neck synovial sarcoma in patients with cervical metastasis.
Methods:
A 20-year-old man was seen with a palpable mass in the right neck. He had been diagnosed with synovial sarcoma of the right tonsil and treated by surgery 1 and a half years before; therefore, the mass detected was thought to be a cervical metastasis of synovial sarcoma. We performed a modified radical neck dissection with no postoperative treatment. The pathological diagnosis was confirmed by detecting the SS-specific fusion gene SYT-SSX1.
Results:
The patient remains free of recurrence or metastasis 2 years and 10 months after the surgery.
Conclusions:
We encountered a case of head and neck synovial sarcoma with cervical metastasis that was successfully treated.
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