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Related Concept Videos

Assembly of Cytoskeletal Filaments01:18

Assembly of Cytoskeletal Filaments

Cytoskeletal filaments are polymeric forms of smaller protein subunits. However, individual cytoskeletal filaments may easily disassemble or associate with other similar filaments to form rigid structures. Microfilaments, made of actin monomers, rely on actin-binding proteins to form bundles and create networks of individual actin filaments. Microtubules rely on microtubule-associated proteins (MAPs) to form sturdy cylindrical structures. However, the proteins involved in forming complex...
Assembly of Complex Microtubule Structures01:32

Assembly of Complex Microtubule Structures

Complex microtubule structures are present in resting cells and in dividing cells. In resting cells, they are responsible for maintaining the cellular architecture, tracks for intracellular transport, positioning of organelles, assembly of cilia and flagella. They mediate the bipolar spindle assembly for chromosomal segregation and positioning of the cell division plate in dividing cells. The formation of microtubule complex structures depends on the cell type, cell stage, and cell function.
Micelles01:30

Micelles

Micelle formation is an intricate process that hinges on the properties of amphiphilic or amphipathic molecules and the conditions of the system in which they are found. Amphiphilic molecules, which have both hydrophilic (water-attracting) and hydrophobic (water-repelling) parts, play a critical role in this process.In aqueous environments, these molecules arrange themselves such that their hydrophilic heads are turned towards the water phase, while their hydrophobic tails are oriented away...
Formation of Higher-order Actin Filaments01:11

Formation of Higher-order Actin Filaments

The polymerization of G-actin monomers into filamentous F-actin is a multi-step process. Once the F-actins are formed, they can bundle together in different arrangements to form higher-order networks and regulate cellular functions. Common examples include the formation of lamellipodia and filopodia at the cell's leading edge by actin reorganization in a migrating cell. The microvilli on the brush border epithelial cells are also formed through the F-actin network.
The high-order actin networks...
Protein Complex Assembly02:41

Protein Complex Assembly

Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...
The Colloidal State01:29

The Colloidal State

The formation of a colloidal system is exemplified by an aqueous solution containing Cl− ions is introduced to another containing Ag+ ions, resulting in the precipitation of solid AgCl as extremely tiny crystals. Instead of settling out as a filterable precipitate, these crystals remain suspended in the liquid, showcasing a colloidal system.A colloidal system involves colloidal particles within the approximate range of 1 to 1000 nm in at least one dimension, dispersed in a medium called the...

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Updated: Jul 3, 2026

Liquid-cell Transmission Electron Microscopy for Tracking Self-assembly of Nanoparticles
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Published on: October 16, 2017

Hierarchical self-assembly of nematic colloidal superstructures.

M Skarabot1, M Ravnik, S Zumer

  • 1J Stefan Institute, Jamova 39, Ljubljana, Slovenia.

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
|July 23, 2008
PubMed
Summary

Colloidal particles self-assemble into superstructures within liquid crystals. Small particles decorate defect rings formed by large particles, a concept applicable to nanoscale assembly.

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Area of Science:

  • Colloidal science
  • Soft matter physics
  • Materials science

Background:

  • Nematic liquid crystals exhibit unique defect structures.
  • Colloidal particles interact with these defects.
  • Controlling colloidal assembly is crucial for materials design.

Purpose of the Study:

  • To demonstrate colloidal superstructure formation in nematic liquid crystals.
  • To utilize elastic interactions for directed self-assembly.
  • To explore nanoscale applications of this assembly method.

Main Methods:

  • Simulations of colloidal particle mixtures in nematic liquid crystals.
  • Analysis of elastic interactions between small particles and disclination lines.
  • Modeling the decoration of topological defect matrices.

Main Results:

  • Colloidal superstructures were successfully assembled.
  • Small particles decorated defect rings and loops formed by large particles.
  • The self-assembly concept was shown to be extendable to nanoscale particles.

Conclusions:

  • Colloidal self-assembly in nematics is achievable through defect-mediated interactions.
  • This method offers precise control over superstructure formation.
  • The findings pave the way for nanoscale colloidal assembly and novel materials.