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Hyperbaric oxygen therapy for radiation-induced hemorrhagic cystitis
Takahiro Yoshida1, Atsunari Kawashima, Takeshi Ujike
1Department of Urology, Osaka Rosai Hospital, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan. takahiro-y@sannet.ne.jp
Hyperbaric oxygen (HBO) therapy effectively manages radiation-induced hemorrhagic cystitis. This treatment resolved hematuria in 75% of patients, with no noted side-effects, making it a viable option.
Area of Science:
- Urology
- Oncology
- Hyperbaric Medicine
Background:
- Hemorrhagic cystitis is a debilitating side effect of radiation therapy.
- Hyperbaric oxygen (HBO) therapy is emerging as a potential treatment option.
Purpose of the Study:
- To review the efficacy and safety of HBO therapy for radiation-induced hemorrhagic cystitis.
Main Methods:
- Retrospective review of eight patients with radiation-induced hemorrhagic cystitis treated with HBO therapy between 2001 and 2007.
- Patients received HBO therapy for a mean duration of 8.9 months post-hematuria onset.
- Mean follow-up was 15.5 months.
Main Results:
- Complete hematuria resolution in six of eight patients (75% response rate).
- One patient experienced recurrence and responded to a second HBO course.
- No significant side-effects of HBO therapy were reported.
Conclusions:
- HBO therapy is a safe and effective treatment for radiation-induced hemorrhagic cystitis.
- It should be considered as a primary management option for this condition.
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