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Updated: Jul 3, 2026
09:53
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Primary myxomas of the skull base
Summary
This study reviews twelve cases of intracranial primary myxomas, rare skull base tumors. Radical excision is recommended, though recurrence is common for these cranial nerve affecting tumors.
Area of Science:
- Neurosurgery
- Pathology
- Oncology
Background:
- Intracranial primary myxomas are rare extradural tumors originating from the skull base.
- These tumors often present with a chronic course and unilateral cranial nerve dysfunction.
- Diagnosis prior to surgery can be challenging.
Purpose of the Study:
- To review the clinical characteristics, management, and outcomes of intracranial primary myxomas.
- To highlight the rarity and diagnostic challenges associated with these tumors.
- To discuss the optimal treatment strategies for skull base myxomas.
Main Methods:
- Retrospective review of 12 cases of intracranial primary myxomas treated between 1983 and 1992.
- All cases involved surgical excision and histological confirmation.
- Clinical echocardiography was performed to rule out cardiac myxoma.
Main Results:
- The mean age at presentation was 34.2 years, with a male predominance (7/12).
- All tumors were extradural and located at the skull base.
- Radical surgical excision was performed, but recurrence was noted as a tendency.
Conclusions:
- Intracranial primary myxomas are rare, challenging to diagnose preoperatively, and require radical surgical excision.
- Despite complete resection, these tumors demonstrate a propensity for recurrence.
- Further discussion in neurosurgical literature is warranted for these skull base neoplasms.
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