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Updated: Jul 3, 2026
10:32
Detection of Post-Replicative Gaps Accumulation and Repair in Human Cells Using the DNA Fiber Assay
Published on: February 3, 2022
Genomic stability: FANCJ-dependent G4 DNA repair
1Department of Immunology, University of Washington School of Medicine, 1959 NE Pacific St., Seattle, Washington 98195-7650, USA. maizels@u.washington.edu
Current Biology : CB
|July 23, 2008
Abstract:
G-rich regions have the potential to form G4 DNA upon replication, which can lead to genomic instability. FANCJ, a G4 DNA helicase, has been shown to be critical for the stability of regions that match the G4 signature motif by experiments analyzing its nematode homolog.
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