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Related Experiment Video

Updated: Jul 3, 2026

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

Published on: December 4, 2020

Genitourinary tuberculosis in pediatric urological practice.

R B Nerli¹, G V Kamat, S B Alur

¹Department of Urology, KLES Kidney Foundation, KLES Prabhakar Kore Hospital & MRC, Nehru Nagar, Belgaum 590010, India. rbnerli@yahoo.com

Journal of Pediatric Urology

|July 23, 2008

Summary

Genitourinary tuberculosis in children is rare and often presents with vague symptoms. Prompt diagnosis and a combination of antitubercular therapy and surgery lead to satisfactory outcomes, especially with reconstructive procedures.

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Establishment and Characterization of UTI and CAUTI in a Mouse Model

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Published on: June 23, 2015

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Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice

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Published on: December 4, 2020

Establishment and Characterization of UTI and CAUTI in a Mouse Model

Establishment and Characterization of UTI and CAUTI in a Mouse Model

Published on: June 23, 2015

Area of Science:

Pediatric infectious diseases
Urology
Public health

Background:

Genitourinary tuberculosis (GUTB) is a rare secondary form of tuberculosis, often presenting with subtle symptoms in children.
Antitubercular therapy is the primary treatment, with surgery reserved for a subset of cases.

Purpose of the Study:

To evaluate the clinical features, treatment, and outcomes of genitourinary tuberculosis in pediatric patients.
To emphasize the role of surgical intervention in managing pediatric GUTB.

Main Methods:

Retrospective review of case records for 17 children diagnosed with genitourinary tuberculosis.
Analysis of clinical presentation, organ involvement, diagnostic investigations, treatment modalities, and patient outcomes.

Main Results:

The most common presentation was lower urinary tract symptoms, with the ureter being the most frequently involved organ (41%).
Mycobacterium tuberculosis was identified in only 29% of urinary examinations.
A total of 28 surgical procedures were performed, including endoscopic, ablative, and reconstructive techniques. Renal function improved or stabilized in 80% of affected children.

Conclusions:

Genitourinary tuberculosis in children exhibits diverse clinical and pathological features, often leading to delayed diagnosis.
Combined antitubercular drug therapy and judicious surgical management yield positive results.
Advances in reconstructive surgery, particularly using bowel segments, offer promising outcomes, necessitating rigorous follow-up for pediatric patients.