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Multi-Modal Home Sleep Monitoring in Older Adults

Multi-Modal Home Sleep Monitoring in Older Adults

Published on: January 26, 2019

Renal function and sleep-disordered breathing in older men.

Muna T Canales¹, Li-Yung Lui, Brent C Taylor

¹Department of Medicine, University of Florida, Division of Nephrology, Hypertension and Renal Transplantation, Gainesville, FL 32610, USA. muna.canales@medicine.ufl.edu

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association

|July 23, 2008

Summary

Reduced kidney function in older men was not linked to sleep-disordered breathing (SDB). The association observed in younger old men was primarily due to higher body mass index, not kidney disease itself.

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Area of Science:

Nephrology
Sleep Medicine
Geriatrics

Background:

Sleep-disordered breathing (SDB) is prevalent in severe chronic kidney disease (CKD), potentially increasing morbidity and mortality.
The relationship between mild to moderate CKD and SDB risk remains unclear.
Investigating SDB in CKD is crucial for managing patient outcomes.

Purpose of the Study:

To examine the association between reduced renal function and SDB in older men.
To determine if mild to moderate CKD influences the likelihood of SDB.
To explore potential confounding factors in this relationship.

Main Methods:

Utilized data from 2696 men aged 65+ from the MrOS Sleep study.
Assessed chronic kidney disease (CKD) using estimated glomerular filtration rate (eGFR) calculated from serum creatinine.
Diagnosed sleep-disordered breathing (SDB) via respiratory disturbance index (RDI) and oxygen desaturation during polysomnography (PSG).

Main Results:

No significant association was found between lower eGFR and higher RDI in the overall cohort.
An interaction between eGFR and age suggested a potential link in younger old men (
This association in younger old men was not statistically significant after adjusting for body mass index (BMI).

Conclusions:

Reduced renal function in older men is not independently associated with increased SDB.
Higher BMI appears to be a significant factor mediating the link between lower eGFR and SDB in younger old men.
Further research in younger populations is warranted to fully elucidate these findings.