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Updated: Jul 3, 2026

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
Published on: September 27, 2024
Long-term results of carbon dioxide laser resurfacing of the face
1Department of Otolaryngology-Head and Neck Surgery, University of Michigan, 1904 Taubman Center, 1500 E Medical Center Dr, Ann Arbor, MI 48109, USA. pdanielw@med.umich.edu
Objective:
To evaluate the long-term effectiveness of, and the complications associated with, carbon dioxide laser treatment of rhytidosis and solar aging.
Methods:
This retrospective report describes our experience with 47 patients who underwent entire facial carbon dioxide laser resurfacing.
Results:
The mean improvement in facial rhytid score at long-term follow-up was 45%. This improvement was consistent in all facial subsites. With the exception of 1 case of hyperpigmentation, which resolved within 2 years of treatment, hypopigmentation was the only long-term adverse effect. This complication was present in 6 patients (13%). The patients who developed hypopigmentation were more likely to have a greater response to treatment.
Conclusion:
Our findings show that carbon dioxide laser resurfacing is a safe and effective treatment for facial rhytids.

