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Kluyvera infections in the pediatric population
J Elliot Carter1, Javier A Laurini, Kelly N Mizell
1Department of Pathology, University of South Alabama, Mobile, AL 36617, USA. ecarter@usouthal.edu
The Pediatric Infectious Disease Journal
|July 23, 2008
Summary
Kluyvera species infections are increasingly recognized in children, causing illnesses from soft tissue infections to severe sepsis. While effective treatments exist, antibiotic resistance is a growing concern for this emerging pathogen.
Area of Science:
- Medical Microbiology
- Pediatric Infectious Diseases
- Antimicrobial Resistance
Background:
- Kluyvera species are increasingly identified as a significant cause of infections in pediatric populations.
- The spectrum of disease ranges from localized soft tissue infections to life-threatening sepsis with multiorgan failure.
Purpose of the Study:
- To highlight the emerging clinical importance of Kluyvera species in pediatric infections.
- To inform clinicians about the spectrum of disease and effective treatment options.
Main Methods:
- This study is a review of current literature on Kluyvera species infections in children.
- Analysis of reported cases and treatment outcomes.
Main Results:
- Kluyvera species infections present a diverse clinical picture in pediatric patients.
- Effective treatments include third-generation cephalosporins, tetracycline, aminoglycosides, and fluoroquinolones.
- Resistance to first- and second-generation cephalosporins is noted, emphasizing the need for appropriate antibiotic selection.
Conclusions:
- Kluyvera species represent an emerging pathogen in pediatric infectious diseases.
- Awareness of the clinical spectrum and antimicrobial susceptibility patterns is crucial for effective management.
- Clinicians must consider Kluyvera species in the differential diagnosis of pediatric infections and select treatments judiciously.
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