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Updated: Jul 3, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
[Parathyroid carcinoma: multicenter study of 17 patients]
S Mucci-Hennekinne1, G Desolneux, F Luyckx
1Service de chirurgie viscérale et endocrinienne, CHU Angers - Angers.
Purpose Of The Study:
To evaluate clinical characteristics and survival of patients treated for parathyroid carcinoma.
Study Design:
A retrospective multicenter chart review of patients treated for parathyroid carcinoma between January 1979 and January 2005.
Results:
17 patients (10 women, 7 men) presenting with parathyroid carcinoma underwent surgical resection. Symptoms were largely related to hypercalcemia. Mean postoperative follow-up was seven years. Local recurrence was noted in four patients (24%) and three patients had late distant metastasis (18%). At the end of the study, nine patients were alive without evidence of recurrence (53%) and one patient was alive with recurrence at 5 years. Seven patients had died, four of whom died as a result of their parathyroid disease.
Conclusion:
Even when symptoms and findings are suggestive, the diagnosis of parathyroid carcinoma is oftentimes difficult. An adequate resection at the first intervention (complete tumor resection including a homolateral thyroid lobectomy and parathyroidectomy with resection of central lymph nodes) is recommended.
