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Related Concept Videos

Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.

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Related Experiment Video

Updated: Jul 3, 2026

The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve
09:51

The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve

Published on: September 7, 2022

Cognitive function and cerebral emboli after primary hip arthroplasty.

A C Gray1, L Torrens, C R Howie

  • 1Orthopaedic and Trauma Department, Edinburgh Royal Infirmary, Edinburgh, UK. andrewgray@doctors.org.uk

Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
|July 23, 2008
PubMed
Summary

Cognitive function, particularly mental processing speed and attention, may be affected after hip arthroplasty. However, cerebral embolic signals detected during surgery did not correlate with cognitive changes in this study.

Related Experiment Videos

Last Updated: Jul 3, 2026

The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve
09:51

The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve

Published on: September 7, 2022

Area of Science:

  • Neurosurgery
  • Orthopedic Surgery
  • Cognitive Neuroscience

Background:

  • Cerebral emboli can occur during hip arthroplasty, but their impact on cognitive function remains unclear.
  • Transcranial Doppler ultrasound is used to monitor these embolic events.

Purpose of the Study:

  • To assess cognitive changes following primary cemented hip arthroplasty.
  • To measure intraoperative cerebral embolic load using Transcranial Doppler ultrasound.
  • To investigate the relationship between embolic load and cognitive dysfunction.

Main Methods:

  • Twenty patients undergoing primary cemented total hip arthroplasty were evaluated.
  • Cognitive tests assessed global function, verbal fluency, memory, attention, and processing speed before and after surgery.
  • Intraoperative Transcranial Doppler ultrasound monitored middle cerebral artery embolic signals.

Main Results:

  • Significant differences were observed in mental processing speed, visual searching, and attention post-surgery (p<0.01).
  • Cerebral embolic signals were detected in 11 of 20 patients, primarily during cementation and hip reduction.
  • No significant cognitive difference was found between patients with and without detectable embolic signals.
  • No direct correlation was identified between embolic load size and the degree of cognitive dysfunction.

Conclusions:

  • Hip arthroplasty can lead to measurable changes in specific cognitive functions, such as processing speed and attention.
  • Intraoperative cerebral embolic signals detected via Transcranial Doppler ultrasound do not appear to be directly linked to the observed cognitive changes or dysfunction after hip arthroplasty.