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A Method to Assess Bacteriocin Effects on the Gut Microbiota of Mice
Published on: July 25, 2017
[Antimicrobial susceptibility of probiotics]
Jin Xu1, Xiumei Liu, Baolan Yang
1Institute of Nutrition and Food Safety, China Center for Control and Prevention, Beijing 100021, China.
Abstract:
The aim of our study was to analyse the antibiotic susceptibility of 31 probiotics strains, including 9 Bifidobacterium and 22 Lactobacillus used for the manufacture of various fermented foods in China. Probiotics are tested for minimum inhibitory concentrations (MIC) of 24 kinds of antibiotics by broth dilution method on cation-adjusted Mueller-Hinton broth with lysed horse blood. 31 strains of probiotics were sensitive to ampicillin, penicillin, imipenem, gentamicine, amoxicillin, amoxicillin/clavulanic acid, gatifloxacin, erythromycin, clindamycin, and resistant to nalidixic acid, vancomycine, fosfomycin.
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