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Published on: November 24, 2020
Risk factors for dyslipidemia in Chinese children
1Department of Pediatrics, Peking University First Hospital, Beijing 100034, People' Republic of China.
Insights
This study identified key risk factors for dyslipidemia in Chinese children, including elevated body mass index (BMI), waist-to-height ratio (WHR), and diastolic blood pressure. Familial history also significantly increases risk, highlighting the need for early screening and intervention.
Area of Science:
- Pediatric Endocrinology
- Cardiovascular Health
- Public Health
Background:
- Cardiovascular disease mortality is rising, increasing focus on dyslipidemia in pediatric populations.
- Understanding dyslipidemia risk factors in children is crucial for early intervention and prevention.
Purpose of the Study:
- To investigate the prevalence and risk factors of dyslipidemia in Chinese children.
- To identify anthropometric and clinical indicators associated with dyslipidemia in this demographic.
Main Methods:
- A cross-sectional study involving 962 children aged 6-18 years in Beijing.
- Data collection included anthropometric measurements (height, weight, BMI, WHR), blood pressure, serum lipid levels, and family history.
- Statistical analyses, including logistic regression, were used to determine risk factors.
Main Results:
- The prevalence of dyslipidemia was 11.1% among the studied children.
- Children with dyslipidemia showed significantly higher sitting height, upper arm circumference, BMI, WHR, and diastolic/systolic blood pressure.
- Logistic regression identified WHR, diastolic blood pressure, and a positive familial history as significant risk factors.
Conclusions:
- Elevated BMI, WHR, diastolic blood pressure, and a family history of dyslipidemia are significant risk factors for dyslipidemia in Chinese children.
- These findings underscore the importance of monitoring these parameters for early detection and management of pediatric dyslipidemia.
Aim:
Since the mortality rate due to cardiovascular disease continues to increase, research into dyslipidemia has been emphasized in not only adults but also paediatric populations. We aimed to study the risk factors of dyslipidemia in Chinese children.
Methods:
Nine hundred and sixty-two children, aged 6-18 years, in Beijing were enrolled. For each child, data were collected on body height (cm), body weight (kg), sitting height (cm), waist circumference, upper arm circumference, serum lipid levels, as well as familial history of dyslipidemia and early onset cardiovascular disease. Subgroups were determined on the basis of age and sex.
Results:
The prevalence rate of dyslipidemia was 11.1% (107/962). Children with dyslipidemia differed significantly from those without, in sitting height, upper arm circumference, body mass index (BMI), waist-to-height ratio (WHR) and diastolic and systolic blood pressure (p < 0.05). Logistic regression analysis suggested that WHR, diastolic blood pressure and positive familial history were risk factors for dyslipidemia in children.
Conclusion:
Sitting height, upper arm circumference, BMI, WHR, diastolic pressure and systolic pressure were significantly higher in dyslipidemic children than in normal subjects in China. BMI, WHR, diastolic pressure and familial history of dyslipidemia and early-onset cardiovascular disease were risk factors for dyslipidemia in Chinese children.
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