Related Experiment Video
Updated: Jul 3, 2026
Tri-layered Electrospinning to Mimic Native Arterial Architecture using Polycaprolactone, Elastin, and Collagen: A Preliminary Study
Published on: January 4, 2011
Generation of multilayered structures for biomedical applications using a novel tri-needle coaxial device and
1Department of Mechanical Engineering, University College London, Torrington Place, London WC1E 7JE, UK. ucemzah@ucl.ac.uk
Abstract:
In this short communication, we describe the scope and flexibility of using a novel device containing three coaxially arranged needles to form a variety of novel morphologies. Different combinations of materials are subjected to controlled flow through the device under the influence of an applied electric field. The resulting electrohydrodynamic flow allows us to prepare double-layered bubbles, porous encapsulated threads and nanocapsules containing three layers. The ability to process such multilayered structures is very significant for biomedical engineering applications, for example, generating capsules for drug delivery, which can provide multistage controlled release.
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