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Dual-source CT for visualization of the coronary arteries in heart transplant patients with high heart rates
Gorka Bastarrika1, Carlo Nicola De Cecco, Maria Arraiza
1Department of Radiology, Clínica Universitaria, Universidad de Navarra, Ave. Pío XII, 36, 31008 Pamplona, Spain. bastarrika@unav.es
Insights
Dual-source CT coronary angiography provides diagnostic quality images in heart transplant recipients, even with high heart rates. Image quality is not negatively impacted by heart rate or its variability during scanning.
Area of Science:
- Cardiovascular Imaging
- Radiology
- Transplant Medicine
Background:
- Heart transplant recipients often experience elevated heart rates.
- Assessing coronary artery health is crucial in these patients.
- Dual-source CT (DSCT) is a key imaging modality.
Purpose of the Study:
- To evaluate the diagnostic quality of DSCT coronary angiography.
- To assess image quality in heart transplant recipients with high heart rates.
Main Methods:
- DSCT coronary angiography performed on 23 heart transplant recipients.
- Image analysis by two independent readers using a 5-point scale.
- Data reconstruction across various R-R intervals.
Main Results:
- High interobserver agreement for image quality assessment (kappa=0.78).
- Diagnostic image quality achieved in 92.1% of coronary segments.
- No significant correlation found between heart rate/variability and image quality.
Conclusions:
- DSCT angiography yields diagnostic quality coronary images in heart transplant recipients.
- Elevated heart rate and heart rate variability do not adversely affect image quality.
Objective:
The purpose of this study was to evaluate the quality of dual-source CT images of the coronary arteries in heart transplant recipients with high heart rates.
Subjects And Methods:
Contrast-enhanced dual-source CT coronary angiography was performed on 23 heart transplant recipients (20 men, three women; mean age, 61.1 +/- 12.8 years). Data sets were reconstructed in 5% steps from 30% to 80% of the R-R interval. Two blinded independent readers using a 5-point scale (0, not evaluative; 4, excellent quality) assessed the quality of images of coronary segments.
Results:
The mean heart rate during scanning was 89.2 +/- 10.4 beats/min. Interobserver agreement on the quality of images of the whole coronary tree was a kappa value of 0.78 and for selection of the optimal reconstruction interval was a kappa value of 0.82. The optimal reconstruction interval was systole in 17 (74%) of the 23 of heart transplant recipients. At the best reconstruction interval, diagnostic image quality (score >or= 2) was obtained in 92.1% (303 of 329) of the coronary artery segments. The mean image quality score for the whole coronary tree was 3.1 +/- 1.01. No significant correlation between mean heart rate (rho = 0.31) or heart rate variability (rho = 0.23) and overall image quality score was observed (p = not significant).
Conclusion:
Dual-source CT acquisition yields coronary angiograms of diagnostic quality in heart transplant recipients. Mean heart rate and heart rate variability during scanning do not have a negative effect on the overall quality of images of the coronary arteries.
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