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Nutrition support in acute pancreatitis
Orestis Ioannidis1, Athina Lavrentieva, Dimitrios Botsios
1Fourth Surgical Department, Medical School, Aristotle University, Thessaloniki, Greece. telonakos@yahoo.gr
JOP : Journal of the Pancreas
|July 24, 2008
Summary
Enteral nutrition is preferred for acute pancreatitis patients, offering a cheaper, safer, and more effective approach compared to total parenteral nutrition. This method helps reduce complications and hospitalization, improving patient outcomes.
Area of Science:
- Gastroenterology
- Critical Care Medicine
- Surgical Nutrition
Background:
- Acute pancreatitis is often self-limiting, but severe cases involve systemic inflammation and organ dysfunction.
- Positive nitrogen balance is crucial for survival in severe acute pancreatitis.
- Nutritional support aims to meet metabolic demands without exacerbating pancreatic autodigestion.
Purpose of the Study:
- To evaluate the effectiveness of enteral nutrition (EN) via jejunal administration in acute pancreatitis patients.
- To compare EN with total parenteral nutrition (TPN) in terms of safety, efficacy, and cost.
Main Methods:
- Controlled clinical studies comparing jejunal EN with TPN.
- Assessment of immunoinflammatory response, septic complications, need for surgery, and hospitalization duration.
Main Results:
- Enteral nutrition was found to be cheaper, safer, and more effective than TPN.
- EN suppressed immunoinflammatory response and decreased septic complications.
- EN reduced the need for surgery and shortened total hospitalization periods.
- No significant difference was observed in mortality or non-septic complications between EN and TPN.
Conclusions:
- Enteral nutrition via jejunal administration is the preferred route for nutritional support in acute pancreatitis.
- EN offers significant advantages over TPN in managing severe acute pancreatitis.
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