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Updated: Jul 3, 2026

Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy
Published on: August 25, 2019
Double aneuploidy in spontaneous miscarriages: two case reports and review of the literature
Umit Korucuoglu1, Mehmet Erdem, Elif Pala
1Department of Obstetrics and Gynecology, Gazi University Faculty of Medicine, Ankara, Turkey. korucu23@yahoo.com
Abstract:
The occurrence of double aneuploidy is a relatively rare phenomenon. The clinical presentations are variable depending on the predominating aneuploidy or a combination effect of both. We report the cytogenetic data on products of conception from miscarriages over a period of 5 years. A total of 403 miscarriages were karyotyped and the tissues were villi in all cases. Of 403 cases, 54 cases with single aneuploidy and 2 cases of first-trimester miscarriages with double trisomies were found. These 2 cases with the karyotypes of 48,XXY,+15 and 48,XX,+5,+7 were cited for the first time in this study.
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