Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ophthalmologic complications in hemoglobinopathies.

K W To1, A J Nadel

  • 1Department of Ophthalmology, Lenox Hill Hospital, Cornell University Medical College, New York, New York.

Hematology/Oncology Clinics of North America
|June 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sequencing of Pleural Fluid and Plasma for Tuberculous Pleuritis.

NEJM evidence·2026
Same author

Validation of diagnosis codes for pleural diseases and procedure codes for relevant respiratory procedures in a healthcare database in Hong Kong: a single tertiary centre study.

Hong Kong medical journal = Xianggang yi xue za zhi·2026
Same author

A review of reported cases of HIV pre-exposure prophylaxis failure with resultant breakthrough HIV infections.

HIV medicine·2020
Same author

Increasing the coverage of influenza vaccination in healthcare workers: review of challenges and solutions.

The Journal of hospital infection·2016
Same author

Comparison of empirical continuous positive airway pressure (CPAP) treatment versus initial portable sleep monitoring followed by CPAP treatment for patients with suspected obstructive sleep apnoea.

Internal medicine journal·2010
Same author

Depressive symptoms among community-dwelling, post-stroke elders in Hong Kong.

International nursing review·2010

Sickle cell disease causes red blood cell sickling and blood vessel blockages. Regular eye exams are crucial for early detection and treatment of vision-threatening ophthalmic complications.

Area of Science:

  • Ophthalmology
  • Hematology
  • Genetics

Background:

  • Sickle cell disease (SCD) is a group of inherited blood disorders characterized by abnormal hemoglobin.
  • This abnormality leads to red blood cell sickling, particularly under hypoxic conditions, causing vaso-occlusion.
  • Ophthalmic manifestations are common in SCD, affecting various eye structures.

Purpose of the Study:

  • To review the ophthalmic manifestations of sickle cell disease.
  • To emphasize the importance of regular ophthalmological examinations for early detection and management.
  • To highlight the link between specific SCD genotypes and the severity of ocular complications.

Main Methods:

  • Review of existing literature on sickle cell disease and its ocular complications.

Related Experiment Videos

  • Analysis of clinical observations regarding the prevalence and types of eye conditions in SCD patients.
  • Comparison of ophthalmic severity across different sickle cell disease genotypes (SC disease, SB thalassemia, SS disease).

    • Main Results:

    • Ophthalmic complications affect the conjunctiva, iris, retina, and optic nerve in sickle cell disease patients.
    • Patients with SC disease and SB thalassemia often experience more severe ophthalmic issues compared to those with SS disease.
    • Peripheral retinal disease, if untreated, can lead to severe vision loss through retinal detachments and vitreous hemorrhages.

    Conclusions:

    • Early identification and treatment of peripheral retinal disease are essential for preserving vision in sickle cell disease patients.
    • Periodic eye examinations by ophthalmologists are critical for managing ocular complications.
    • Prompt intervention can prevent irreversible visual impairment in individuals with sickle cell disease.