Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Vector Algebra: Graphical Method01:10

Vector Algebra: Graphical Method

Vectors can be multiplied by scalars, added to other vectors, or subtracted from other vectors. The vector sum of two (or more) vectors is called the resultant vector or, for short, the resultant.
We use the laws of geometry to construct resultant vectors, followed by trigonometry to find vector magnitudes and directions. For a geometric construction of the sum of two vectors in a plane, we follow the parallelogram rule. Suppose two vectors are at arbitrary positions. Translate either one of...
pV-Diagrams01:18

pV-Diagrams

The pV diagram, which is a graph of pressure versus volume of the gas under study, is helpful in describing certain aspects of the substance. When the substance behaves like an ideal gas, the ideal gas equation describes the relationship between its pressure and volume. On a pV diagram, it is common to plot an isotherm, which is a curve showing p as a function of V with the number of molecules and the temperature fixed. Then, for an ideal gas, the product of the pressure of the gas and its...
Network Covalent Solids02:18

Network Covalent Solids

Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
Graphs of Functions01:30

Graphs of Functions

Graphs of functions provide a visual representation of how output values change in response to varying inputs. Each point on the graph corresponds to an ordered pair, where the x-coordinate (independent variable) determines the horizontal position and the y-coordinate (dependent variable) determines the vertical position. Linear functions like y = x give a straight line, indicating a constant rate of change.Nonlinear functions display more complex behaviors. Even power functions generate...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The impact of age factors on postoperative limb function recovery in breast cancer.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2026
Same author

IL-10 affects mechanism of intervertebral disc degenerative lesions treated with curcumin by regulating the MAPK signaling pathway.

Pakistan journal of pharmaceutical sciences·2026
Same author

From text to translation: using language models to prioritize variants for clinical review.

Genome medicine·2026
Same author

Efficacy and Safety of Massage Therapy for Cognitive Impairment in Patients With Autism Spectrum Disorder: Protocol for a Systematic Review and Meta-Analysis.

JMIR research protocols·2026
Same author

Language models reveal evidence gaps in variants of uncertain significance.

medRxiv : the preprint server for health sciences·2026
Same author

Endovascular Treatment in Stroke Patients of Working Age: A Multicenter Observational Study of Real-World Outcomes.

Therapeutics and clinical risk management·2025
Same journal

Modeling and analysis of forward and inverse kinematics for a flexible Stewart platform.

PloS one·2026
Same journal

Barriers and facilitators to healthcare utilization amongst people living with sickle cell disease in the United States: A scoping review.

PloS one·2026
Same journal

Enhancing data completeness in time series: Imputation strategies for missing data using significant periodically correlated components.

PloS one·2026
Same journal

Key targets and mechanisms by which gut microbiota-derived metabolites regulate Alzheimer's disease through the immune - inflammatory pathway: Based on network pharmacology and molecular docking.

PloS one·2026
Same journal

Grid-tied Transformer-less Boost Switched Capacitor Topology (TLBSCT) for PV applications.

PloS one·2026
Same journal

The load-velocity profiles and exercise-specific velocity zones for seven commonly used weightlifting exercises.

PloS one·2026
See all related articles

Related Experiment Video

Updated: Jul 3, 2026

Recording and Analyzing Multimodal Large-Scale Neuronal Ensemble Dynamics on CMOS-Integrated High-Density Microelectrode Array
09:44

Recording and Analyzing Multimodal Large-Scale Neuronal Ensemble Dynamics on CMOS-Integrated High-Density Microelectrode Array

Published on: March 8, 2024

Visualizing global properties of large complex networks.

Weijiang Li1, Hiroyuki Kurata

  • 1School of Biotechnology, Southern Yangtze University, Wuxi, China.

Plos One
|July 24, 2008
PubMed
Summary
This summary is machine-generated.

We developed a novel Circular Perspective Drawing (CPD) method to visualize complex biological networks, revealing global structures and organizational principles of large protein interaction networks.

More Related Videos

Soft Pneumatic Robot Modulates Graph Theory Metrics of Brain Network for Hand Rehabilitation After Stroke
05:30

Soft Pneumatic Robot Modulates Graph Theory Metrics of Brain Network for Hand Rehabilitation After Stroke

Published on: October 10, 2025

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms
08:51

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms

Published on: November 1, 2019

Related Experiment Videos

Last Updated: Jul 3, 2026

Recording and Analyzing Multimodal Large-Scale Neuronal Ensemble Dynamics on CMOS-Integrated High-Density Microelectrode Array
09:44

Recording and Analyzing Multimodal Large-Scale Neuronal Ensemble Dynamics on CMOS-Integrated High-Density Microelectrode Array

Published on: March 8, 2024

Soft Pneumatic Robot Modulates Graph Theory Metrics of Brain Network for Hand Rehabilitation After Stroke
05:30

Soft Pneumatic Robot Modulates Graph Theory Metrics of Brain Network for Hand Rehabilitation After Stroke

Published on: October 10, 2025

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms
08:51

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms

Published on: November 1, 2019

Area of Science:

  • Complex biological networks
  • Systems biology
  • Bioinformatics

Background:

  • Understanding complex biological networks requires effective visualization tools.
  • Existing methods struggle to capture the topology of large, heterogeneous networks like protein interaction networks.

Purpose of the Study:

  • To introduce a new method for visualizing global structures of large complex networks.
  • To aid in understanding the design principles of biological networks.

Main Methods:

  • Circular Perspective Drawing (CPD) method.
  • Combines quasi-continuous search (QCS) with random node swapping.
  • Enhances calculation speed for large networks.

Main Results:

  • CPD visualizes global network structures effectively.
  • Depicts connection patterns between network parts, not just individual links.
  • Reveals global structural features for better network understanding.

Conclusions:

  • CPD offers a novel approach to visualizing complex biological networks.
  • Facilitates comprehensive understanding of network organization.
  • Aesthetic representation aids in identifying key network patterns.