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TGF - β Signaling Pathway

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The TGF-β signaling pathway regulates cell growth, differentiation, adhesion, motility, and development. TGF-β ligands that induce TGF-β signaling are synthesized in their latent form. Several proteases or cell surface receptors such as integrins act upon the latent form, releasing the active ligand. There are three types of mammalian TGF-βs: (TGF-β1, TGF-β2, and TGF-β3) that bind as homodimers or heterodimers to TGF-β receptors. The TGF-β receptors...

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Related Experiment Video

Updated: Jan 10, 2026

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells

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Published on: October 27, 2020

Assays for transforming growth factor beta

¹Division of Immunobiology, National Institute for Biological Standards and Control, Potters Bar, Herts, U.K.

Journal of Immunological Methods

|July 26, 1991

Summary

No abstract available in PubMed .

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