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Analyses of Actin Dynamics, Clutch Coupling and Traction Force for Growth Cone Advance
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ERM proteins regulate growth cone responses to Sema3A.

C David Mintz1, Ioana Carcea, Daniel G McNickle

  • 1Fishberg Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA.

The Journal of Comparative Neurology
|July 25, 2008
PubMed
Summary

Ezrin, radixin, and moesin (ERMs) coordinate axonal growth cone responses to Semaphorin 3A (Sema3A) guidance cues. These proteins regulate receptor internalization and actin dynamics, crucial for growth cone collapse and directed growth.

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