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Green Synthesis of Quinoline-Based Ionic Liquid
Published on: September 27, 2024
"Nonsolvent" applications of ionic liquids in biotransformations and organocatalysis
1AkzoNobel BV, Chemicals Process and Product Technology Department, Velperweg 76, P.O. Box 9300, 6800 SB Arnhem, The Netherlands. pablo.dominguez@akzonobel.com
Abstract:
The application of room-temperature ionic liquids (RTILs) as (co)solvents and/or reagents is well documented. However, RTILS also have "nonsolvent" applications in biotransformations and organocatalysis. Examples are the anchoring of substrates to RTILs; ionic-liquid-coated enzymes (ILCE) and enzyme-IL colyophilization; the construction of biocatalytic ternary reaction systems; the combination of enzymes, RTILs, membranes, and (bio)electrochemistry; and ionic-liquid-supported organocatalysts. These strategies provide more robust, more efficient, and more enantioselective bio- and organocatalysts with many practical applications. As shown herein, RTILs offer a wide range of promising alternatives to conventional chemistry.
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