Related Experiment Video

Updated: Jul 3, 2026

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1
11:56

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1

Published on: August 24, 2015

[Clinical and structural comparisons in a child with disseminated herpetic infection]

L M Shchugareva, N A Il'ina, E Iu Kriukov

    Vestnik Rentgenologii I Radiologii
    |July 26, 2008
    PubMed

    Insights

    Diagnosing herpes infections in infants is challenging due to vague symptoms and immature immune systems. Neurovisual methods are becoming crucial for identifying severe brain herpes infections like encephalitis.

    Area of Science:

    • Pediatrics
    • Virology
    • Neurology

    Background:

    • Herpes virus infections are common in children.
    • Diagnosing herpes in infants presents challenges due to subtle symptoms and immune system immaturity.
    • Brain herpes infections, such as encephalitis, represent the most severe manifestation.

    Observation:

    • Neurovisual diagnostic methods are increasingly utilized.
    • Techniques include transcranial ultrasonography and computed tomography (CT).
    • These methods aid in the detection of herpetic encephalitis.

    Findings:

    • The study highlights the growing importance of neurovisual techniques.
    • These methods assist in diagnosing severe neurological complications of herpes infections in infants.
    • Early and accurate diagnosis is critical for effective treatment.

    Implications:

    • Increased reliance on neurovisual methods can improve diagnostic accuracy for infant herpes encephalitis.
    • Enhanced diagnostic capabilities may lead to better patient outcomes.
    • Further research into neurovisual methods for pediatric herpes infections is warranted.

    More Related Videos

    Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection07:55

    Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection

    Published on: November 3, 2012

    Related Concept Videos

    Genital Herpes01:23

    Genital Herpes

    Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...
    Herpes01:28

    Herpes

    Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...
    Chickenpox01:20

    Chickenpox

    Chickenpox is an acute, highly contagious disease caused by the varicella-zoster virus (VZV), a double-stranded DNA virus belonging to the Herpesviridae family. Its transmission occurs primarily through the inhalation of respiratory droplets or direct contact with vesicular fluid from skin lesions. The incubation period typically ranges from 10 to 21 days, during which the virus replicates and disseminates through sequential phases within the host. Although generally self-limiting in children,...
    Cytomegalovirus Disease01:27

    Cytomegalovirus Disease

    Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
    Encephalitis ll: Pathophysiology01:26

    Encephalitis ll: Pathophysiology

    Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
    Endocarditis II: Clinical Features of Infective Endocarditis01:25

    Endocarditis II: Clinical Features of Infective Endocarditis

    Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...