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Published on: June 8, 2022
[Sdudy on effect of tripterygium on plasma IL-18 content in patients with lupus nephritis]
Cai-Yun Jin1, Guo-Hua Hu, Bi-Zhong Zheng
1Department of dermatology, School of Medicine, Taizhou College, Taizhou 318000, China.
Objective:
It is to study the effect of tripterygium (TW) on the plasma IL-18 content in patients with lupus nephritis (LN) and its treatment value.
Method:
The patients with LN treated with prednisone were divided into active groupand inactive group with active index. The active group was given tripterygium additionally. The changing of plasma IL-18 and release of nephritis were observed after treatment for three months.
Result:
The level of plasma IL-18 lowered down obviously, urinary protein decreased, LN activity index, hematuria and renal function improved.
Conclusion:
Tripterygium caninhibitroduction of plasma IL-18. It has definite treatment value on controlling LN activity.