Related Experiment Video
Updated: Jul 3, 2026

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
Published on: June 3, 2020
Morbidity patterns in aged population in southern Italy. A survey sampling
F Cacciatore1, C Gallo, N Ferrara
1Istituto di Medicina Interna, Cardiologia e Chirurgia Cardiovascolare, Università degli Studi di Napoli Federico II, Via S. Pansini 5, 80131 Naples, Italy.
This study on elderly individuals in Southern Italy found high rates of chronic illness (91.3%), cognitive impairment (27.9%), and disability (46.7% in daily activities). Comorbidity and disability increased with age, particularly in women.
Area of Science:
- Gerontology
- Public Health
- Epidemiology
Background:
- The elderly population faces significant health challenges including chronic diseases, cognitive decline, and disability.
- Understanding the prevalence of these conditions is crucial for developing targeted healthcare interventions.
Purpose of the Study:
- To investigate the prevalence of disability, cognitive impairment, depressive symptomatology, and chronic diseases in an elderly Mediterranean population.
- To analyze the relationship between these health issues and age.
Main Methods:
- A cross-sectional study was conducted on 1339 elderly subjects in Southern Italy.
- Health assessments included the Mini-Mental State Examination (MMSE) for cognition, Geriatric Depression Scale (GDS) for depression, and Activities of Daily Living (ADL/IADL) for disability.
- Prevalence of 10 specific chronic diseases was recorded.
Main Results:
- 27.9% exhibited cognitive impairment (MMSE <24), with scores declining with age.
- 9.8% had severe depression (GDS >20).
- Only 8.7% were free of chronic illness; 26.6% had four or more conditions. Disability affected 7% in ADL and 46.7% in IADL, increasing with age and more prevalent in females.
Conclusions:
- The study highlights a high burden of chronic diseases, cognitive impairment, depression, and disability in the elderly Southern Italian population.
- Age is a significant factor associated with increased comorbidity and disability.
- Gender disparities in disability prevalence were observed.
Related Concept Videos
Pharmacodynamics in Geriatric Patients: Effects of Age
Bias in Epidemiological Studies
Drug Dosing: Geriatric Patients
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Prevalence and Incidence
Prevalence indicates the proportion of individuals in a population who have a specific disease or health condition at a...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption