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Stereotactic Radiosurgery for Gynecologic Cancer
Published on: April 17, 2012
Gamma knife radiosurgery for orbital tumors
Min-Su Kim1, Kwan Park, Jong Hyun Kim
1Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Clinical Neurology and Neurosurgery
|July 26, 2008
Summary
Gamma Knife Radiosurgery (GKS) shows promise for treating orbital tumors, achieving tumor control in most patients. Multisession radiosurgery may enhance visual function preservation, especially for tumors near the optic nerve.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Ophthalmology
Background:
- Orbital tumors present complex treatment challenges.
- Gamma Knife Radiosurgery (GKS) is an established treatment for intracranial lesions.
Purpose of the Study:
- To evaluate radiological and functional outcomes of orbital tumors treated with GKS.
- To assess the efficacy of single-session versus multisession GKS for orbital tumors.
Main Methods:
- Retrospective analysis of 15 patients with diverse orbital tumors treated with GKS.
- Tumor types included meningiomas, hemangiomas, schwannomas, metastatic tumors, and adenoid cystic carcinoma.
- Radiosurgery details: single-session (median 14Gy) and multisession (median 20Gy) for tumors near the optic nerve.
Main Results:
- Tumor control achieved in 12 out of 15 patients after a mean follow-up of 20.9 months.
- Three patients with malignant tumors required reoperation due to progression.
- Among 13 patients with preserved preoperative vision, 6 improved, 4 remained stable, and 3 experienced deterioration.
Conclusions:
- GKS is a potentially effective treatment for orbital tumors, similar to intracranial applications.
- Multisession radiosurgery is a viable strategy for preserving visual function in select orbital tumor cases adjacent to the optic apparatus.
