Related Experiment Video
Updated: Jul 3, 2026

Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
Published on: December 4, 2020
An unusual cause of vaginal discharge following gender reassignment
S Sukumaran1, P A Moran, A Makar
1Department of Obstetrics and Gynaecology, Worcester Royal Hospital, Worcester, UK. suganya15_11@yahoo.co.in
Abstract:
Neovaginal reconstruction is an important part of gender reassignment surgery. We report a case of stone formation at the apex of vaginal vault constructed with sigmoid colon segment. A 48-year-old woman presented with profuse vaginal discharge for 1 year. She had a history of gender reassignment surgery (male to female) in 1994, and the neovagina had been constructed with an isolated sigmoid colon. Vaginoscopy performed using a cystoscope revealed multiple calculi at the vaginal vault on the endoscopic gastrointestinal anastomosis staples that had been used to close the vault. Colon-vaginoplasty has the advantages of providing adequate lubrication, but excessive vaginal discharge could be a problem, as colon is a mucous membrane. Stone formation in the vaginal vault should be considered in cases of gender reassignment with persistent vaginal discharge. This case also highlights the use of cystoscope in visualising the upper vagina in difficult circumstances.
Related Concept Videos
Microbiota of the Urogenital Tract
Disorders of the Female Reproductive System
Trichomoniasis
Candidiasis
External Female Genitals
Vagina
