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Updated: Jul 3, 2026

Comparing Metastatic Clear Cell Renal Cell Carcinoma Model Established in Mouse Kidney and on Chicken Chorioallantoic Membrane

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Published on: February 8, 2020

[Vaginal metastasis from renal cell carcinoma].

L Osório¹, F Sabell, J Soares

¹Servicio de Urología, Hospital General Santo Antonio, Porto, Portugal. lposorio@gmail.com

Actas Urologicas Espanolas

|July 29, 2008

Summary

Vaginal metastases from renal cell carcinoma (RCC) are rare. This case highlights that unexplained vaginal masses in women may indicate metastatic RCC, emphasizing the need for thorough investigation of renal origins.

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A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

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Published on: April 12, 2017

Area of Science:

Oncology
Urology
Gynecologic Oncology

Background:

Renal cell carcinoma (RCC) is a malignant tumor originating in the kidneys.
Metastatic spread of RCC to the vagina is exceptionally rare.
Understanding diverse metastatic patterns is crucial for accurate diagnosis and treatment.

Observation:

A 75-year-old woman presented with hematuria and vaginal pain.
Diagnostic workup identified a primary renal tumor and a distinct vaginal mass.
The patient underwent nephrectomy and vaginal mass excision.

Findings:

Histopathological analysis confirmed metastatic renal cell carcinoma in the vaginal mass.
The case demonstrates an unusual presentation of advanced RCC.
Clear cell carcinoma of the vagina is rare and can be secondary to renal tumors.

Implications:

This case underscores the importance of considering renal malignancy in patients with unexplained vaginal lesions.
It highlights the diagnostic challenges posed by rare metastatic presentations of RCC.
Clinicians should maintain a high index of suspicion for renal origins in vaginal clear cell carcinoma.