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Comparative hypersensitivity in intravenous lipid emulsions.

A L Buchman¹, M E Ament

¹Division of Pediatric Gastroenterology and Nutrition, University of California Los Angeles Medical Center 90024-1752.

JPEN. Journal of Parenteral and Enteral Nutrition

|May 1, 1991

Summary

A patient experienced hypersensitivity to Intra-lipid, but not Liposyn II, likely due to protein contamination. This highlights a potential cause for allergic reactions to lipid emulsions.

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Area of Science:

Clinical Immunology
Nutritional Science
Pharmaceutical Manufacturing

Background:

Intra-lipid and Liposyn II are common lipid emulsions used in parenteral nutrition.
Hypersensitivity reactions to lipid emulsions, though rare, can occur.
Patient had a history of mild allergies to soybean protein and eggs.