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Persistent interface fluid syndrome.

Richard S Hoffman1, I Howard Fine, Mark Packer

  • 1Hoffman & Packer LLC, Eugene, OR 97403, USA. rshoffman@finemd.com <rshoffman@finemd.com>

Journal of Cataract and Refractive Surgery
|July 29, 2008
PubMed
Summary
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Persistent interface fluid after corneal transplant was resolved by repositioning the laser in situ keratomileusis flap. Scarring at the graft-host margin may have caused this intractable fluid, requiring surgical intervention.

Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Interface Fluid Management

Background:

  • Persistent interface fluid is a rare complication following corneal transplantation.
  • Descemet-stripping endothelial keratoplasty (DSEK) is a common procedure for corneal endothelial dysfunction.
  • Standard management often fails to resolve persistent interface fluid.

Observation:

  • A case of intractable interface fluid is presented.
  • The fluid persisted despite normal intraocular pressure.
  • Corneal endothelial replacement with DSEK did not resolve the fluid.

Findings:

  • Surgical intervention involving dissection, elevation, and repositioning of the laser in situ keratomileusis (LASIK) flap was necessary.
  • This intervention successfully resolved the persistent interface fluid.

Related Experiment Videos

  • Circumferential corneal graft-host margin scar formation was hypothesized as the cause.

    • Implications:

    • This case highlights a potential cause of intractable interface fluid after corneal surgery.
    • Repositioning of a LASIK flap may be a viable treatment option in refractory cases.
    • Understanding scar formation mechanics is crucial for managing post-keratoplasty fluid accumulation.