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Key articles and guidelines in the management of hypertension: 2008 update

Sarah M Gaffney1, Simon de Denus, Kari L Olson

  • 1Department of Pharmacy, Northeast Georgia Health System, 743 Spring Street, Gainesville, GA 30501, USA.

Pharmacotherapy
|July 29, 2008
PubMed

Insights

This review summarizes key hypertension management literature from 2003-2007. It updates previous guidelines on pharmacologic and nonpharmacologic treatments for cardiovascular disease risk reduction.

Area of Science:

  • Cardiology
  • Pharmacology
  • Clinical Practice

Background:

  • Hypertension is a significant risk factor for cardiovascular disease.
  • Effective management relies on extensive published research.
  • Previous guidelines were published in 2004.

Purpose of the Study:

  • To provide an updated synopsis of key literature on hypertension management.
  • To review clinical trials, meta-analyses, and practice guidelines.
  • To inform pharmacologic and nonpharmacologic treatment strategies.

Main Methods:

  • Literature review of publications from May 2003 to June 2007.
  • Inclusion of clinical trials and meta-analyses.
  • Synopsis of clinical practice guidelines.

Main Results:

  • Compilation of synopses on hypertension management literature.
  • Focus on evidence published between 2003 and 2007.
  • Update to the 2004 "Key Articles and Guidelines in the Management of Hypertension."

Conclusions:

  • The updated review provides current evidence for hypertension treatment.
  • Informs optimal pharmacologic and nonpharmacologic therapeutic choices.
  • Aids clinicians in managing cardiovascular disease risk.

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