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Study of distortion-product otoacoustic emissions during hypothermia in humans
Aim:
To evaluate the function of cochlear outer hair-cells under the influence of extra-corporeal circulation and moderate hypothermia during cardiac surgery.
Study Design:
Prospective clinical study.
Methods:
Distortion-product otoacoustic emissions (DPOAE) were registered before surgery, immediately after general anesthesia induction, during extra-corporeal circulation with moderate hypothermia and after the surgical procedure.
Results:
Comparison of response-amplitudes before and after surgery and before and after general anesthesia initiation did not demonstrate statistical difference. Comparison of amplitudes before and after extra-corporeal circulation with moderate hypothermia demonstrated a statistically significant decrease in responses amplitudes during hypothermia.
Conclusions:
The amplitudes of DPOAE decreased during moderate hypothermia induced during extra-corporeal circulation.
