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Does selective intubation increase ablation zone size during pulmonary cryoablation?

J Louis Hinshaw1, Lisa Sampson, Fred T Lee

  • 1Department of Radiology, University of Wisconsin, E3/311 CSC, 600 Highland Ave, Madison, WI 53792, USA. jhinshaw@uwhealth.org

Journal of Vascular and Interventional Radiology : JVIR
|July 30, 2008
PubMed
Summary

Selective bronchial intubation did not significantly alter ablation zone size in pulmonary cryoablation. This suggests the technique may not be necessary for this procedure, unlike radiofrequency ablation.

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Area of Science:

  • Pulmonary Medicine
  • Interventional Pulmonology
  • Cryoablation Technology

Background:

  • Pulmonary cryoablation is an emerging technique for treating lung lesions.
  • Selective bronchial intubation is used in other lung ablation procedures to control ventilation.

Purpose of the Study:

  • To investigate the impact of selective bronchial intubation and aeration on ablation zone characteristics during pulmonary cryoablation.

Main Methods:

  • Domestic swine underwent selective bronchial intubation and aeration.
  • Twenty pulmonary cryoablations were performed (10 ventilated, 10 non-ventilated).
  • Ablation zone dimensions, circularity, and volume were measured post-excision.

Main Results:

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  • No significant differences were observed in ablation zone diameter, area, circularity, or estimated volume between ventilated and non-ventilated groups.
  • Mean diameter was 2.4 cm in both groups (P = .99).
  • Mean area was 4.6 cm² vs 4.8 cm² (P = .7), and mean volume was 11.5 cm³ vs 11.3 cm³ (P = .99).

    • Conclusions:

    • Selective bronchial intubation does not significantly affect ablation zone size in pulmonary cryoablation.
    • Unlike radiofrequency ablation, this technique may not be beneficial for pulmonary cryoablation.
    • Findings suggest selective intubation is likely not warranted for pulmonary cryoablation procedures.