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Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
12:59

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes

Published on: September 26, 2013

Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor

Lorenzo Cosmi1, Raffaele De Palma, Veronica Santarlasci

  • 1Department of Internal Medicine and DENOTHE Center, University of Florence, Florence 50134, Italy.

The Journal of Experimental Medicine
|July 30, 2008
PubMed
Summary

CD161 is a novel surface marker for human interleukin-17 T helper (Th17) cells. All IL-17-producing cells originate from CD161-positive naive CD4+ T cells, implicating CD161 in Th17 cell development.

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