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Related Concept Videos

Preclinical Development: Overview01:28

Preclinical Development: Overview

Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
Drug Discovery: Overview01:26

Drug Discovery: Overview

Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
Drug Regulation01:25

Drug Regulation

Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
Drug Administration and Therapy Phases: Overview01:26

Drug Administration and Therapy Phases: Overview

Drugs, the chemical agents used in diagnosing, treating, or preventing diseases, undergo a four-phase process of development: pharmaceutic, pharmacokinetics, pharmacodynamics, and therapeutic.
The pharmaceutical phase focuses on leveraging the physicochemical properties of the drug to design and manufacture an effective product. Variants include orally administered tablets or capsules, topical creams or ointments, and parenteral-delivery solutions or emulsions.
The pharmacokinetic phase...
Prodrugs01:30

Prodrugs

Prodrugs are a class of pharmaceutical compounds that undergo a biotransformation process within the body to be converted into a pharmacologically active drug. Prodrugs are designed to improve the therapeutic properties of the parent drug, such as enhancing bioavailability, increasing stability, or reducing toxicity. The concept of prodrugs revolves around modifying the chemical structure of the original drug to make it more effective or convenient for administration.
Prodrugs help overcome...
Biopharmaceutics and Pharmacokinetics: Overview01:28

Biopharmaceutics and Pharmacokinetics: Overview

Understanding drugs, drug products, and their performance in pharmaceutical science is pivotal. Drugs, whether simple molecules or complex compounds, are designed to interact with the body's biological systems to diagnose, treat, or prevent diseases. Drug products include various delivery systems such as tablets, capsules, injections, and inhalers. The performance of these drug products is gauged by their ability to deliver the active ingredient to the desired site of action at the appropriate...

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Related Experiment Video

Updated: Jul 3, 2026

Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules
09:55

Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules

Published on: October 4, 2024

Animal pharming, two decades on.

Alexander Kind1, Angelika Schnieke

  • 1Livestock Biotechnology, Technische Universität München, Center of Life and Food Sciences Weihenstephan, Hochfeldweg, 1, Freising 85354, Germany.

Transgenic Research
|July 30, 2008
PubMed
Summary

Animal pharming uses transgenic animals for biopharmaceutical production, with the first therapeutic product approved in 2006. Despite advancements, it remains a niche market, potentially succeeding with unique transgenic products.

Area of Science:

  • Biotechnology
  • Pharmaceutical Sciences
  • Animal Genetics

Background:

  • The animal pharming industry has utilized transgenic animals for biopharmaceutical production for two decades.
  • The first regulatory approval for a transgenic biopharmaceutical product was achieved in 2006, marking a significant milestone.

Purpose of the Study:

  • To assess the current status and future prospects of the animal pharming industry.
  • To address skepticism regarding investor confidence and societal acceptance of transgenic livestock for biopharmaceutical manufacturing.

Main Methods:

  • Review of industry progress, technological developments, and regulatory frameworks.
  • Analysis of market trends in biopharmaceuticals and the position of animal pharming.

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Production and Testing of Antimicrobial Peptides and Their Mimics

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Main Results:

  • A novel production platform and groundbreaking technologies have been developed.
  • A necessary regulatory framework for transgenic products has been established.
  • Animal pharming, despite cost advantages, currently operates as a niche production method.

Conclusions:

  • The animal pharming industry has made considerable strides, with a growing biopharmaceutical market offering optimism.
  • Long-term success may hinge on the development of products uniquely achievable through transgenic animals.