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Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
Published on: July 18, 2017
[Actinomycosis of the kidney: a case report]
R Homberg1, W Cherri, J Woziwodzki
1Ammerland-Klinik GmbH, Klinik für Urologie und Kinderurologie, Westerstede. roland.homberg@ammerlandklinik.de
Abstract:
Actinomycosis is a rare infection mainly of the head and neck region (cervicofacial actinomycosis). The cause of this infection is bacterial invasion of the host's mucosal barrier with consecutive infiltration of the surrounding tissues. The treatment of choice after diagnosis is a prolonged course of high-dose antibiotics. The presence of abdominal actinomycosis is at a maximum of 25%, whereas renal involvement appears only sporadically. Aggravating causes for early diagnosis are the appearance of abscesses, fistulae and a debilitating illness resembling carcinoma and leading to surgery as the treatment of choice. Renal actinomycosis is a diagnostic challenge because it is included in the differential diagnosis of renal masses with coexisting B-symptoms. The suspicion requires surgical treatment--nephrectomy. We report on a patient who was transferred to our department for nephrectomy because of radiologically diagnosed renal and perirenal abscesses. The histological result showed renal actinomycosis.
Insights
Actinomycosis is a rare bacterial infection. This case highlights renal actinomycosis, a challenging diagnosis often requiring nephrectomy, presenting as renal masses.
Area of Science:
- Infectious Diseases
- Urology
- Pathology
Background:
- Actinomycosis is a rare bacterial infection, predominantly affecting the head and neck (cervicofacial actinomycosis).
- Renal actinomycosis is exceptionally rare, complicating the diagnosis of renal masses and often mimicking carcinoma.
- Diagnosis is challenging due to non-specific symptoms and the need for advanced imaging and histology.
Observation:
- The case involved a patient referred for nephrectomy due to suspected renal and perirenal abscesses.
- Radiological findings suggested abscesses, necessitating surgical intervention.
- Histological examination confirmed the presence of renal actinomycosis.
Findings:
- Histological confirmation of renal actinomycosis in a patient presenting with suspected renal abscesses.
- The infection presented as renal and perirenal abscesses, leading to a nephrectomy recommendation.
- This case underscores the diagnostic difficulty of renal actinomycosis.
Implications:
- Highlights the importance of considering actinomycosis in the differential diagnosis of renal masses, especially with B-symptoms.
- Suggests that while antibiotics are standard, surgical intervention like nephrectomy may be required for renal actinomycosis.
- Emphasizes the need for thorough histological examination for definitive diagnosis of rare infections like renal actinomycosis.
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