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Related Experiment Videos

The functioning liver mass.

G Molino1

  • 1Dipartimento di Fisiopatologia Clinica, Università degli Studi di Torino.

La Ricerca in Clinica E in Laboratorio
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

This review explores functioning liver mass, integrating anatomical, histological, and biochemical factors. It proposes a clinical protocol using galactose elimination capacity and D-sorbitol clearance to assess liver metabolic mass and plasma flow.

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Area of Science:

  • Hepatology
  • Physiology
  • Biochemistry

Background:

  • Liver function arises from complex anatomical, histological, and biochemical interactions.
  • Functioning liver mass is a virtual parameter reflecting the integrated biological processes of the liver.
  • Understanding liver mass requires considering biochemical transformations, membrane, and intraluminal transports.

Purpose of the Study:

  • To categorize functioning liver mass based on its diverse biological aspects and interactions.
  • To review parameters for evaluating static and dynamic aspects of functioning liver mass.
  • To propose a clinical protocol for assessing liver function.

Main Methods:

  • Categorization of functioning liver mass by transport mechanisms (biochemical, membrane, intraluminal) and interactions (intracellular, transcellular, transacinar, flow-dependent).

Related Experiment Videos

  • Consideration of static and dynamic parameters reflecting liver mass, characterized by capacity or activity.
  • Discussion of methods for evaluating functioning liver mass.

    • Main Results:

    • Functioning liver mass is multifaceted, involving various transport systems and interactions.
    • Parameters for liver mass evaluation can be static or dynamic, providing capacity or activity estimates.
    • A clinical protocol combining galactose elimination capacity and D-sorbitol clearance is proposed.

    Conclusions:

    • Assessing liver function requires a comprehensive view of functioning liver mass.
    • The proposed clinical protocol offers a method to evaluate both metabolic liver mass and functional hepatic plasma flow.
    • This approach aids in a more complete understanding of liver health and disease.