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Updated: Jul 3, 2026

Sample Drift Correction Following 4D Confocal Time-lapse Imaging
Published on: April 12, 2014
Fast, exact k-space sample density compensation for trajectories composed of rotationally symmetric segments, and the
Dimitris Mitsouras1, Robert V Mulkern, Frank J Rybicki
1Cardiovascular Imaging Section, Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts, USA. dmit-souras@alum.mit.edu
Abstract:
A recently developed method for exact density compensation of non uniformly arranged samples relies on the analytically known cross-correlations of Fourier basis functions corresponding to the traced k-space trajectory. This method produces a linear system whose solution represents compensated samples that normalize the contribution of each independent element of information that can be expressed by the underlying trajectory. Unfortunately, linear system-based density compensation approaches quickly become computationally demanding with increasing number of samples (i.e., image resolution). Here, it is shown that when a trajectory is composed of rotationally symmetric interleaves, such as spiral and PROPELLER trajectories, this cross-correlations method leads to a highly simplified system of equations. Specifically, it is shown that the system matrix is circulant block-Toeplitz so that the linear system is easily block-diagonalized. The method is described and demonstrated for 32-way interleaved spiral trajectories designed for 256 image matrices; samples are compensated non iteratively in a few seconds by solving the small independent block-diagonalized linear systems in parallel. Because the method is exact and considers all the interactions between all acquired samples, up to a 10% reduction in reconstruction error concurrently with an up to 30% increase in signal to noise ratio are achieved compared to standard density compensation methods.
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