Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Esophageal Perforation-I: Introduction

Esophageal Perforation-I: Introduction

Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus.

Tooth Anatomy

Tooth Anatomy

The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.

Peptic Ulcer

Peptic Ulcer

Peptic ulcers are erosive lesions of the gastric or duodenal lining, most commonly caused by Helicobacter pylori infection. This Gram-negative, helical bacterium has adapted to survive the stomach’s acidic environment by producing urease, which converts urea into ammonia and carbon dioxide. The ammonia neutralizes gastric acid in the bacterium’s immediate environment, allowing colonization of the gastric mucosa. H. pylori attaches to mucus-secreting epithelial cells, penetrates the mucus...

Peptic Ulcer Disease I: Introduction

Peptic Ulcer Disease I: Introduction

Peptic ulcer disease (PUD) involves breaks in the gastrointestinal tract's mucosal lining, primarily in the stomach and duodenum, with less frequent occurrences in the lower esophagus or near the pylorus.Ulcers can be acute or chronic. Acute ulcers are short-lived with minimal inflammation and heal quickly after the irritant is removed. Chronic ulcers persist, may recur, and often cause scarring due to ongoing tissue damage. Superficial erosions affect only the mucosal layer and are called...

Peptic Ulcer Disease I: Introduction

Peptic Ulcer Disease I: Introduction

Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...

Intestinal Obstruction II: Pathophysiology

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Long-term follow-up of papillary and follicular thyroid carcinomas with bone metastasis.

PloS one·2017

Same author

Incidental parathyroidectomy during thyroidectomy increases the risk of postoperative hypocalcemia.

The Laryngoscope·2017

Same author

Patient outcomes following surgical management of multinodular goiter: Does multinodularity increase the risk of thyroid malignancy?

Medicine·2016

Same author

Soft tissue invasion of papillary thyroid carcinoma.

Clinical & experimental metastasis·2016

Same author

Therapeutic Outcome of Second Primary Malignancies in Patients with Well-Differentiated Thyroid Cancer.

International journal of endocrinology·2016

Same author

Surgical management of substernal goitres at a tertiary referral centre: A retrospective cohort study of 2,104 patients.

International journal of surgery (London, England)·2016

Search research articles

Related Experiment Video

Updated: Jul 3, 2026

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research

Published on: October 27, 2023

Perforation of the duodenum by an ingested toothbrush.

Hsiao-Hsiang Chao¹, Tzu-Chieh Chao

¹Department of Surgery, Chang Gung Memorial Hospital, 5 Fuhsing Street, Kweishan, Taoyuan 33305, Taiwan, China.

World Journal of Gastroenterology

|July 31, 2008

Summary

A rare case of duodenal perforation caused by an ingested toothbrush handle is presented. Surgical removal was successful, with no complications, highlighting a unique cause of gastrointestinal injury.

More Related Videos

Handheld Metal Detector Screening for Metallic Foreign Body Ingestion in Children

Handheld Metal Detector Screening for Metallic Foreign Body Ingestion in Children

Published on: September 11, 2018

Related Experiment Videos

Last Updated: Jul 3, 2026

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research

Published on: October 27, 2023

Handheld Metal Detector Screening for Metallic Foreign Body Ingestion in Children

Handheld Metal Detector Screening for Metallic Foreign Body Ingestion in Children

Published on: September 11, 2018

Area of Science:

Gastroenterology
Surgical Case Reports

Background:

Foreign body ingestion is a common cause of gastrointestinal distress.
Ingestion of sharp or long objects poses a significant risk of perforation.

Observation:

A 22-year-old female presented with epigastric pain following ingestion of a 12-cm toothbrush handle.
Endoscopic removal from the duodenum was unsuccessful.
Laparotomy identified a perforation in the duodenal bulb.

Findings:

Surgical exploration revealed a duodenal perforation caused by the ingested toothbrush handle.
The foreign body was successfully removed via the perforation.
The duodenal perforation was debrided and surgically closed without complications.

Implications:

This case underscores the potential for unusual foreign bodies to cause serious gastrointestinal injury.
Highlights the importance of considering ingested foreign objects in patients with unexplained abdominal pain.
Emphasizes surgical intervention as a viable option when endoscopic management fails for duodenal perforations.