Crossed cheiro-oral syndrome.
Wei-Hsi Chen1, Tzu-Hui Li, Tsung-Hwa Chen
1Department of Neurology, Chang Gung Memorial Hospital-Kaohsiung Medical Center, and School of Medicine, Chang Gung University, 123 Tai Pei Road, Niao Sung Hsiang, Kaohsiung County 833, Taiwan. e49130@ms14.hinet.net
Clinical Neurology and Neurosurgery
|August 1, 2008
Summary
Crossed cheiro-oral syndrome, a rare sensory disturbance affecting the face and opposite hand, indicates medullary involvement. This condition may be an early sign of Wallenberg's syndrome progression.
Area of Science:
- Neurology
- Neuroanatomy
Background:
- Cheiro-oral syndrome typically involves sensory loss in the face and ipsilateral hand due to brainstem lesions.
- A crossed pattern of facial and contralateral hand sensory disturbance is infrequently documented.
Observation:
- This study details four cases of crossed cheiro-oral syndrome, characterized by perioral and contralateral acral paresthesia.
- Neuroanatomic analysis explored the relationship, course, and clinical significance of this crossed pattern.
Findings:
- All patients presented with lateral or dorsolateral medullary infarctions ipsilateral to their facial paresthesia.
- The syndrome is attributed to diagonal lesions in the medulla, affecting trigeminal and spinothalamic tracts.
Implications:
- Crossed cheiro-oral syndrome may represent a milder variant of Wallenberg's syndrome.
- It serves as a predictor of medullary lesions and a potential warning sign for neurological deterioration.
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