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Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes

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[Pregnancy and psychoactives substances: prevalence study based on the declared consumption].

A Dumas¹, C Lejeune, L Simmat-Durand

¹CNRS UMR 8136, Inserm U611, société Cesames, centre de recherche psychotropes, santé mentale, université Paris-Descartes, 45, rue des Saints-Pères, 75270 Paris cedex 06, France. agnesdumas@free.fr

Journal De Gynecologie, Obstetrique Et Biologie De La Reproduction

|August 1, 2008

Summary

This study found lower rates of tobacco and alcohol use among pregnant women in Paris compared to previous French surveys. It also highlights marijuana use and associated risks in this population.

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Area of Science:

Obstetrics and Gynecology
Public Health
Addiction Medicine

Context:

Substance use during pregnancy poses significant risks to both mother and child.
Previous French surveys on substance use in pregnant populations have varying methodologies and results.
Understanding current substance use patterns is crucial for targeted interventions.

Purpose:

To evaluate the prevalence of substance use, including tobacco, alcohol, psychotropic drugs, and illicit drugs, before and during pregnancy.
To identify high-risk groups among pregnant women based on their substance consumption patterns.
To compare current findings with historical data from French surveys.

Summary:

A survey of 245 pregnant women in the Parisian area revealed that 16.3% smoked before pregnancy, with 10.2% continuing during pregnancy.
Alcohol consumption was reported by 40.8% before pregnancy and 25.3% during pregnancy. Psychotropic drug use was 3.7% and marijuana use was 2.4% in the preceding month.
Marijuana consumers, often co-users of alcohol, face significant social and familial difficulties, identifying them as a high-risk group.

Impact:

This study provides novel insights into substance use, particularly marijuana, among French pregnant women.
Findings suggest potential methodological or cultural factors influencing lower reported tobacco and alcohol use compared to prior French studies.
Results can inform public health strategies and prenatal care for substance-using pregnant women.