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Executive function, coping, and behavior in survivors of childhood acute lymphocytic leukemia
Laura K Campbell1, Mary Scaduto, Deborah Van Slyke
1Department of Psychiatry and Neurobehavioral Sciences, University of Virginia Health System, P.O. Box 800223, Charlottesville, VA 22908-0223, USA. lkc3h@virginia.edu
Objective:
To examine the role of executive function in coping and behavioral outcomes in childhood acute lymphocytic leukemia (ALL) survivors.
Methods:
We examined associations among several domains of executive function (working memory, behavioral inhibition, cognitive flexibility, and self-monitoring), coping, and emotional/behavioral problems in 30 children and adolescents ages 10- to 20-years old who completed treatment for ALL and 30 healthy controls matched on age and sex.
Results:
We found partial support for our hypothesis that performance on executive function measures is associated with strategies used to cope with stress, and emotional and behavioral problems in ALL survivors.
Conclusions:
Findings suggest that executive function impairment may be associated with difficulties in coping and emotion regulation in a subgroup of children treated for ALL. Directions for future research on executive function deficits and coping skills in survivors of pediatric ALL are suggested.
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