Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Ethics in Research01:56

Ethics in Research

Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
Ethical Dilemmas II01:30

Ethical Dilemmas II

Resolving an ethical dilemma in healthcare involves a systematic approach that considers every aspect of the issue, respecting both the patient's needs and values and the healthcare professional's ethical obligations. Here are potential steps to resolve an ethical dilemma:
Ethics and Bioethics01:22

Ethics and Bioethics

Ethics is a philosophical study of moral actions. Ethics attempts to determine what is valuable for individuals and society. It examines the rational justification of moral judgments and analyzes what is morally just, fair, and right. Bioethics is a sub-discipline of applied ethics that analyzes the philosophical, social, and legal issues in life sciences and medicine. Ethical theories serve as a foundation for decision-making and represent the viewpoints from which people seek direction. They...
Randomized Experiments01:13

Randomized Experiments

The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
Bias in Epidemiological Studies01:29

Bias in Epidemiological Studies

Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hypoxia-Inducible Factor-1alpha/BNIP3-Mediated Mitochondrial Autophagy in Septic Cardiomyopathy: Protective Mechanism for Cardiac Function.

Physiological research·2026
Same author

Observation of In-Ice Askaryan Radiation from High-Energy Cosmic Rays.

Physical review letters·2026
Same author

Efficient and High-Fidelity Entanglement in Cavity QED without High Cooperativity.

Physical review letters·2026
Same author

Prognostic score models for acquired resistance to frontline anti-programmed cell death protein 1/programmed death-ligand 1 therapy in metastatic non-small-cell lung cancer.

ESMO real world data and digital oncology·2026
Same author

Long-Time Storage of a Qubit Encoded in Decoherence-Free Subspace Using a Dual-Type Quantum Memory.

Physical review letters·2025
Same author

Quantum tomography of a third-order exceptional point in a dissipative trapped ion.

Nature communications·2025

Related Experiment Video

Updated: Jul 3, 2026

E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

Evaluating ethics consultation: randomised controlled trial is not the right tool.

Y-Y Chen1, Y-C Chen

  • 1Department of Bioethics, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA. yxc96@case.edu

Journal of Medical Ethics
|August 1, 2008
PubMed
Summary

Evaluating ethics consultation effectiveness using randomized controlled trials is challenging due to issues with standardization and placebo controls. Further research is needed to overcome these methodological hurdles for reliable results.

More Related Videos

The Adjuvant Efficacy of Angong Niuhuang Pill in the Treatment of Viral Encephalitis: A Meta-Analysis of Randomized Controlled Trials
08:36

The Adjuvant Efficacy of Angong Niuhuang Pill in the Treatment of Viral Encephalitis: A Meta-Analysis of Randomized Controlled Trials

Published on: April 19, 2024

Related Experiment Videos

Last Updated: Jul 3, 2026

E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

The Adjuvant Efficacy of Angong Niuhuang Pill in the Treatment of Viral Encephalitis: A Meta-Analysis of Randomized Controlled Trials
08:36

The Adjuvant Efficacy of Angong Niuhuang Pill in the Treatment of Viral Encephalitis: A Meta-Analysis of Randomized Controlled Trials

Published on: April 19, 2024

Area of Science:

  • Medical Ethics
  • Clinical Research Methodology

Background:

  • Ethics consultation is established in clinical practice, but its effectiveness remains debated.
  • Randomized controlled trials (RCTs) are the gold standard for evaluating clinical interventions.
  • Empirical evidence on the impact of ethics consultation requires rigorous evaluation.

Purpose of the Study:

  • To conduct an integrated review of randomized controlled trials (RCTs) assessing ethics consultation effectiveness.
  • To synthesize findings from high-quality research designs on ethics consultation outcomes.

Main Methods:

  • A systematic search of PubMed was performed for studies utilizing the randomized controlled trial (RCT) design.
  • The search strategy specifically targeted literature on "ethics consultation" and "randomised controlled trial".

Main Results:

  • Four articles met the initial search criteria.
  • One article was excluded as it did not employ a true randomized controlled trial design, leaving three relevant studies for analysis.

Conclusions:

  • Applying randomized controlled trials (RCTs) to evaluate ethics consultation is highly problematic.
  • Key challenges include the lack of standardized ethics consultation protocols and the absence of a suitable placebo to control for placebo effects.
  • These methodological limitations compromise the reliability of results from RCTs and other quantitative research in this field.