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Updated: Jul 3, 2026

Establishment of the Dual Humanized TK-NOG Mouse Model for HIV-associated Liver Pathogenesis
Published on: September 11, 2019
A new indication for liver transplantation: nodular regenerative hyperplasia in human immunodeficiency virus-infected
Mariagrazia Tateo1, Mylène Sebagh, Marie-Pierre Bralet
1Centre Hépato-Biliaire, AP-HP Hôpital Paul Brousse, Villejuif, France.
Abstract:
Nodular regenerative hyperplasia is one of the causes of noncirrhotic portal hypertension and has recently been described in human immunodeficiency virus-infected patients, and the potential role of a prothrombotic state and hepatotoxic antiretroviral medication has been suggested. Moreover, it is now established that liver transplantation is feasible in HIV-infected patients. We describe here our experience concerning 3 HIV-infected patients with severe complications of nodular regenerative hyperplasia treated with liver transplantation.
