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Updated: Aug 8, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

[The characteristics of the clinical course of hereditary hemochromatosis]

L N Valenkevich, O I Iakhontova

    Vrachebnoe Delo
    |May 1, 1991
    PubMed

    The authors describe 32 patients with hemochromatosis observed from 1965 through 1990 (28 men and 4 women). The diagnostic role of serum iron determination and liver biopsy is emphasized. The therapeutic results of bloodletting (500 ml weekly for several years) dyspheral (1-1.2 g intramuscularly daily for 1-2 years and longer). This treatment did not essentially influence the course of diabetes mellitus, liver cirrhosis as well as the articular and endocrine syndromes. The clinical effect of this treatment lasted for 6-8 years.

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