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Related Concept Videos

Analgesia and Pain Management01:25

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
Pain01:20

Pain

Pain serves as a critical warning signal that alerts the body to potential or actual harm. When mechanical pressure on the skin is intense, such as from a sharp pinch, the sensation transitions from touch to pain. Similarly, extreme temperatures, like a hot pot handle, convert the sensation of heat into pain. Pain can also result from overstimulation of other senses, such as blinding light, loud noise, or the intense heat from habañero peppers. This ability to sense pain is essential for...
Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

Opioid Analgesics: Synthetic and Semisynthetic Opioids

Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
Altered States of Awareness01:06

Altered States of Awareness

Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain that...
Nociception01:44

Nociception

Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain. Thus, pain helps the...
General Anesthesia: Overview01:24

General Anesthesia: Overview

Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...

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Related Experiment Video

Updated: Jul 3, 2026

Method for Simultaneous fMRI/EEG Data Collection during a Focused Attention Suggestion for Differential Thermal Sensation
06:33

Method for Simultaneous fMRI/EEG Data Collection during a Focused Attention Suggestion for Differential Thermal Sensation

Published on: January 5, 2014

[Hypnosis and pain perception].

A Vanhaudenhuyse1, P Boveroux, M Boly

  • 1Coma Science Group, Centre de Recherches du Cyclotron, Université de Liège, Liège, Belgique.

Revue Medicale De Liege
|August 2, 2008
PubMed
Summary
This summary is machine-generated.

Hypnosis modulates pain by engaging brain regions like the anterior cingulate and prefrontal cortices. This technique may offer an alternative to general anesthesia for specific surgical procedures.

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An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
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Related Experiment Videos

Last Updated: Jul 3, 2026

Method for Simultaneous fMRI/EEG Data Collection during a Focused Attention Suggestion for Differential Thermal Sensation
06:33

Method for Simultaneous fMRI/EEG Data Collection during a Focused Attention Suggestion for Differential Thermal Sensation

Published on: January 5, 2014

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
14:56

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)

Published on: January 27, 2010

Psychophysically-anchored, Robust Thresholding in Studying Pain-related Lateralization of Oscillatory Prestimulus Activity
07:28

Psychophysically-anchored, Robust Thresholding in Studying Pain-related Lateralization of Oscillatory Prestimulus Activity

Published on: January 21, 2017

Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Medical Hypnosis Research

Context:

  • Advancements in functional neuroimaging techniques provide novel insights into brain activity.
  • Hypnosis is increasingly recognized for its potential role in pain management and altering sensory perception.
  • Previous clinical observations suggest hypnosis can reduce or eliminate the need for general anesthesia in certain surgeries.

Purpose:

  • To explore the neural underpinnings of pain modulation during hypnotic states.
  • To identify specific brain regions, such as the anterior cingulate and prefrontal cortices, involved in hypnotic pain relief.
  • To review evidence supporting the use of hypnosis as an alternative to general anesthesia in surgical settings.

Summary:

  • Functional neuroimaging reveals that hypnosis influences pain perception through activation in the anterior cingulate and prefrontal cortices.
  • These brain regions are critical for processing and modulating sensory and noxious stimuli.
  • Clinical data indicates hypnosis can be a viable alternative to general anesthesia for procedures like thyroidectomy, mastectomy, and plastic surgery.

Impact:

  • Highlights the potential of hypnosis as a non-pharmacological intervention for pain management.
  • Provides a neurobiological basis for understanding how hypnosis affects pain processing.
  • Suggests broader clinical applications for hypnosis in anesthesia and pain control, potentially reducing risks and costs associated with general anesthesia.