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Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune system...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Allergic Reactions02:06

Allergic Reactions

Overview
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

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Related Experiment Video

Updated: Jul 3, 2026

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
06:41

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis

Published on: March 9, 2015

[Association between alopecia areata and atopy].

Emina Kasumagić-Halilović1, Asja Prohić

  • 1Dermatoveneroloska klinika, Klinicki Centar Univerziteta u Sarajevu. kasumagicemina@yahoo.com

Medicinski Arhiv
|August 2, 2008
PubMed
Summary

Alopecia areata (AA), a condition causing patchy hair loss, is significantly linked to atopy, a predisposition to allergic diseases. This study found a higher prevalence of atopy in AA patients compared to those with diffuse hair shedding.

Area of Science:

  • Dermatology
  • Immunology
  • Genetics

Context:

  • Alopecia areata (AA) is a common autoimmune skin condition causing nonscarring hair loss.
  • The exact cause of AA is unknown, but genetic and environmental factors are implicated.
  • Atopy, a tendency towards allergic hypersensitivity, is a known factor in other immune-related conditions.

Purpose:

  • To investigate the statistical association between alopecia areata (AA) and atopy.
  • To compare the prevalence of atopy in AA patients versus a control group with effluvium capillorum (EC).

Summary:

  • The study included 60 AA patients and 50 EC patients, assessing atopy through personal/family history and allergy testing.
  • A significantly higher frequency of atopy was observed in AA patients (30%) compared to the EC control group (10%).

Related Experiment Videos

Last Updated: Jul 3, 2026

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
06:41

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis

Published on: March 9, 2015

  • Specific indicators like personal history of atopy and positive skin tests for allergens were more common in the AA cohort.
  • Impact:

    • Findings suggest a significant link between alopecia areata and atopic constitution.
    • This association may inform future research into the immunopathogenesis of AA.
    • Understanding this link could potentially lead to new diagnostic or therapeutic strategies for AA.