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Establishing Fungal Entomopathogens as Endophytes: Towards Endophytic Biological Control
Published on: April 11, 2013
Bioactive natural products from endophytes: a review
1Shanghai Key Laboratory of Agrobiotechnology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200030, PR China.
Prikladnaia Biokhimiia I Mikrobiologiia
|August 2, 2008
Summary
Endophytic microorganisms living within plants are a rich source of novel bioactive natural products. This review explores these compounds, their functional roles, and challenges in their isolation for medicine and industry.
Area of Science:
- Microbiology
- Natural Product Chemistry
- Pharmacognosy
Background:
- Endophytes are microorganisms inhabiting plant tissues without causing disease.
- They are ubiquitous across plant species and represent a vast, underexplored resource.
- Endophytes are increasingly recognized for producing valuable bioactive compounds.
Purpose of the Study:
- To review bioactive natural products derived from endophytic microorganisms.
- To categorize these products based on their functional roles.
- To discuss the potential and challenges associated with endophyte-derived natural product discovery.
Main Methods:
- Literature review of scientific publications on endophytic microorganisms and their natural products.
- Analysis of reported bioactive compounds and their biological activities.
- Synthesis of information regarding isolation techniques and future prospects.
Main Results:
- Numerous bioactive natural products have been isolated from diverse endophytic microorganisms.
- These compounds exhibit a wide range of activities relevant to medicine, agriculture, and industry.
- The review highlights specific examples of functional roles and applications.
Conclusions:
- Endophytes are a promising source for discovering novel bioactive natural products.
- Further research is needed to overcome challenges in isolating and characterizing these compounds.
- Exploiting endophytes holds significant potential for pharmaceutical, agricultural, and industrial innovations.
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